Search results for "global electron density transfer"

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Unveiling the Ionic Diels-Alder Reactions within the Molecular Electron Density Theory

2021

The ionic Diels–Alder (I-DA) reactions of a series of six iminium cations with cyclopentadiene have been studied within the Molecular Electron Density Theory (MEDT). The superelectrophilic character of iminium cations, ω &gt

Steric effectsCyclopentadienePharmaceutical ScienceIonic bonding010402 general chemistry01 natural sciencesArticleAnalytical Chemistrychemistry.chemical_compoundQD241-441Computational chemistryDrug Discoveryionic Diels–Alder reactionsReactivity (chemistry)Physical and Theoretical Chemistryorganic_chemistry010405 organic chemistryChemistryOrganic ChemistrySolvationCationic polymerizationMolecular Electron Density TheoryIminiumiminium cationsElectron localization function3. Good health0104 chemical sciencesChemistry (miscellaneous)asynchronicityglobal electron density transfersuperelectrophilesMolecular Medicine
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Unveiling the Intramolecular Ionic Diels–Alder Reactions within Molecular Electron Density Theory

2021

The intramolecular ionic Diels–Alder (IIDA) reactions of two dieniminiums were studied within the Molecular Electron Density Theory (MEDT) at the ωB97XD/6-311G(d,p) computational level. Topological analysis of the electron localization function (ELF) of dieniminiums showed that their electronic structures can been seen as the sum of those of butadiene and ethaniminium. The superelectrophilic character of dieniminiums accounts for the high intramolecular global electron density transfer taking place from the diene framework to the iminium one at the transition state structures (TSs) of these IIDA reactions, which are classified as the forward electro density flux. The activation enthalpy ass…

Exergonic reaction010405 organic chemistryChemistryintramolecular ionic Diels–Alder reactionsmolecular electron density theorydieniminiumsIntermolecular forceIminiumIonic bondingGeneral Medicine010402 general chemistry01 natural sciencesElectron localization function0104 chemical sciencesGibbs free energyChemistryCrystallographysymbols.namesakeglobal electron density transferIntramolecular forcesuperelectrophilessymbolsSingle bondQD1-999Chemistry
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